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<font color="#3333ff"><b><big><big><font face="Calisto MT">PharmFacts
E-News Update -- 26 Jul 2010 AD<br>
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<h3><font color="#000000"><small>Please help us carry on our
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conscience.
We also are pulling out the stops to raise extra funds for vitamins and
supplies for pregnancy help centers, and for earthquake victims in
Haiti.<br>
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<h3><small><font color="red">Goal: $50,000; Can you give a sacrificial
gift today? <br>
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<hr size="2" width="100%"><span
style="font-size: 10pt; font-family: arial;"><br>
</span><font face="Verdana" size="2"><font face="Verdana" size="2"><tt><font
color="green"><font face="Calisto MT, serif"><font
face="ARIAL, VERDANA, HELVETICA"><font size="6"><br>
<!--START MAIN HEADLINE--> <img
src="cid:part3.09090203.06080009@pfli.org" width="300"><br>
<a href="http://www.stopforcedabortions.org/">
<u><i><b><font color="RED"><font size="+3">NE LAW SAYS POST-ABORTION
PROBLEMS = LAWSUIT</font></font></b></i></u></a><br>
<br>
</font></font></font></font></tt></font></font><font face="Verdana"
size="2"><font face="Verdana" size="2"><tt><font color="green"><font
face="Calisto MT, serif"><font face="ARIAL, VERDANA, HELVETICA"><font
size="6"><!--START MAIN HEADLINE--> <img
src="cid:part4.09080103.00090502@pfli.org" width="300"><br>
<a
href="http://www.thenownews.com/news/Pharmacist+resigns+from+board/3304326/story.html">
<u><i><b><font color="RED"><font size="+3">CANADIAN PHARMACIST QUITS
BOARD OF PHARMACY TO FIGHT FOR CHANGES...</font></font></b></i></u></a><u><i><b><font
color="RED"><font size="+3"><br>
<a
href="http://www.thenewstribune.com/2010/07/18/1267883/plan-b-plan-irks-gregoire.html">
<u><i><b><font color="RED"><font size="+1">ABORTOHOLIC GREGOIRE FIGHTS
WITH OWN ATTYS OVER PHARMACIST RIGHTS LAWSUIT...</font></font></b></i></u></a><u><i><b><font
color="RED"><font size="+1"><br>
<a
href="http://www.firstthings.com/blogs/secondhandsmoke/2010/07/17/washington-revisits-quashing-of-pharmacy-conscience-rights/">
<u><i><b><font color="RED"><font size="+1">WA STATE REVISITS QUASHING
PHARMACIST CONSCIENCE RIGHTS...</font></font></b></i></u></a></font></font></b></i></u></font></font></b></i></u></font></font></font></font></tt></font></font><br>
<span style="font-size: 10pt; font-family: arial;"><br>
</span>
<hr size="2" width="100%"><font face="Calisto MT"><span
style="font-size: 10pt; font-family: arial;">
<p align="-moz-center"><font size="5"><b><span
style="font-size: 10pt; font-family: arial;"><font size="6">FREEDOM
RIDES FOR THE PREBORN</font>
<font size="6">PROCLAIM HUMAN RIGHTS FOR ALL</font></span></b></font></p>
<p align="start"><b>Washington, DC (23 July 2010)</b> – <i>American
Life League Vice President Jim Sedlak issued the following statement on
the
Pro-Life Freedom Rides scheduled to begin Friday, July 23:<br>
</i><br>
“Our thoughts and prayers are with the Freedom Riders as they
launch an exciting crusade that seeks to bring to the forefront the
need to
secure the equal rights of all human beings. With the blessings of God,
we
hope to see this effort spread across the country and into every
community.<br>
<br>
“Like their forebearers in the civil rights
movement, those embarking on Freedom Rides this weekend will be taking
a
public stand for truth, justice and equal protection under the law.<br>
<br>
“The pro-life movement is indeed the civil rights movement of
the 21st century. More and more Americans are rising up against
oppression
of the weakest and most helpless among us, and taking a stand for
freedom.
Let this Freedom Ride across the country be a clarion call for all
people
of good will to join together to work for the day when America
recognizes
the dignity and personhood of all human beings – in particular, the
preborn and other vulnerable persons.<br>
<br>
“We call on all
Americans to welcome these Freedom Riders with open arms. The time has
come
to recognize the personhood of all people in the town square of every
city.
The time has come for personhood NOW.”<br>
<br>
American Life
League was cofounded in 1979 by Judie Brown. It is the largest
grassroots
Catholic pro-life organization in the United States and is committed to
the
protection of all innocent human beings from the moment of creation to
natural death. For more information or press inquiries, please
contact Katie Walker at 540.659.4942.</p>
<p align="start"><b>FOR MORE INFORMATION:<br>
<br>
Priests for Life:</b>
Pro-Life Freedom Rides Begin in Birmingham (23 July 2010)<br>
<a href="http://ss.all.org/link.php?M=84895&N=923&L=6077&F=H">http://www.priestsforlife.org/action/pro-life-freedom-rides.htm</a></p>
</span></font>
<p><small><b><em><br>
Indiana Planned Parenthood caught on tape giving
fabricated medical
information</em></b><br>
The youth-led pro-life group Live Action released a
new undercover video July 19 showing staff at an Indianapolis Planned
Parenthood clinic using manipulative and medically inaccurate
counseling to
convince a young woman to have an abortion. This is the third
undercover
video Live Action has released showing abusive counseling practices at
Planned Parenthood of Indiana. <br>
<a href="http://ss.all.org/link.php?M=84895&N=924&L=6078&F=H"><font
color="#0000ff">http://www.lifesitenews.com/ldn/2010/jul/10072001.html</font></a></small></p>
<p><small><b><br>
</b><em><b>Despite previous comments on medical treatment, paralyzed
man
really wanted to live</b><br>
</em>A paralyzed man in England who had once
said he would never want to be kept alive were he severely disabled
narrowly escaped death when doctors were about to withdraw treatment.
Though previously unresponsive and in a “very bleak” condition,
he communicated that he wanted to continue to live.<br>
<a href="http://ss.all.org/link.php?M=84895&N=924&L=6082&F=H"><font
color="#0000ff">http://www.ewtn.com/vnews/getstory.asp?number=102751</font></a></small></p>
<p><small><b><br>
<em>New PAV head says attacks on embryo are based in desire for
power</em></b><br>
Attacks on the life and dignity of human embryos are based
on a desire for power, said the recently appointed head of the
Pontifical
Academy for Life (PAV). Monsignor Ignacio Carrasco de Paula said that
from
the viewpoint of science, the ”embryo is very well defended …
The problem is essentially of a socio-political and ideological nature
and
here scientific arguments don’t count … It is a realm in which
what counts is power and if the one who has power has no desire to
dialogue
or at least to reflect somewhat, then he doesn’t have much to do with
other guidelines.” Governments and other groups or individuals that
want to use embryos as living human test subjects “have the
ball,” he said. “That is, in the end what remains is the
political weapon and the political weapon that we citizens have today
is
weak. Those who know politics can do much more and that is their very
grave
responsibility.” <br>
<a href="http://ss.all.org/link.php?M=84895&N=924&L=6079&F=H"><font
color="#0000ff">http://www.lifesitenews.com/ldn/2010/jul/10071601.html</font></a></small></p>
<font id="role_document" color="#000000" face="Arial" size="2"><br>
</font>
<hr size="2" width="100%"><font id="role_document" color="#000000"
face="Arial" size="2"><a
href="http://www.lifeissues.net/writers/irvi/irvi_69ipsstemcell.html">http://www.lifeissues.net/writers/irvi/irvi_69ipsstemcell.html</a><br>
</font>
<div>"Adult stem cells said to 'forget' retooling; Embryonic
alternative [iPS stem cell research] suffers setback"</div>
<div> <font face="Calisto MT"> <br>
</font></div>
<div><font face="Calisto MT">[[<strong>Comments:</strong> While it
would be great of course to find ethical alternatives to the use of
human embryonic stem cells (for therapies and for basic research), the
article copied below indicates once again that scientifically iPS cells
would not constitute that final "ethical alternative". There have also
been several similar research studies over the last few years which
have indicated similar <em>scientific</em> problems with iPS cells.
But there are also a number of <em>ethical</em> concerns that continue
to plague iPS stem cell research. For example: </font></div>
<div><font face="Calisto MT"> </font></div>
<div><font face="Calisto MT">(1) <strong>Referring to iPS stem cells
as "adult" stem cells is very misleading</strong>. Real "adult" stem
cells obtained from adult human tissues and organs are initially
"multipotent", and then are re-programmed to become even <em>more
differentiated</em> cells, whereas iPS cells are obtained from adult
cells that are de-programmed back to "pluripotency" to become <em>far
less differentiated</em> cells. <strong>That is, real "adult" stem
cells are never manipulated to become "pluripotent", whereas iPS stem
cells are.</strong> The ethical concern is that, especially with
little or no control over this de-programming or
de-methylations process (as demonstrated in the studies addressed by
the article below), "totipotent" cells could result instead of
"pluripotent" cells. Since "totipotent" cells are by definition <em>capable</em>
of being reverted to new single cell human embryos by means of the
natural biological process of "regulation" or "de-methylation", if any
totipotent cells do result from these iPS techniques they could
indeed revert back to new single-cell human embryos which would then be
destroyed. Please, this is not to say that all totipotent cells are
embryos (as I have been misquoted as saying). It is to say that the
real possibility exists that such totipotent <em>cells</em> might
revert to new single-cell <em>embryos</em> because they possess the
natural biological process of "regulation" or "de-methylation". Of
interest is that: a) none of these experiments test directly for
"totipotency", only for odd tumor-producing properties of
"pluripotency" -- so they don't know -- empirically -- if any human
embryos have been "accidentally" produced during the iPS process; and
b) their definitions of "pluripotency" and of "totipotency" are
scientifically incorrect. For more details and scientific references
on these concerns, see: </font></div>
<div><font face="Calisto MT"> </font></div>
<div><font face="Calisto MT">Irving, <span>“Pluripotent' Stem Cell
(iPS) Research is Not the Usual 'Adult' Stem Cell Research” (April 8,
2009), at:<span style=""> </span><a
href="http://www.lifeissues.net/writers/irv/irv_138ips_notadultstemcell.html">http://www.lifeissues.net/writers/irv/irv_138ips_notadultstemcell.html</a>;
and, Irving, <span>“Framing the Debates on Human Cloning and Human
Embryonic Stem Cells: Pluripotent vs. TOTIPOTENT” (July 23, 2005), at: <a
href="http://www.lifeissues.net/writers/irv/irv_100debatecloning1.html">http://www.lifeissues.net/writers/irv/irv_100debatecloning1.html</a>.
For related issues of "redefinitions" of standard scientific terms, see
<span style="font-family: 'Arial','sans-serif'; font-size: 10pt;">Irving
and Kischer , “Responses to Dr. Condic's ‘Science’ in <i style="">National
Catholic Register</i> Interview” (January 6, 2010), at:<o:p></o:p></span></span></span></font></div>
<div><font face="Calisto MT"><span
style="font-family: 'Arial','sans-serif'; font-size: 10pt;"><a
href="http://www.lifeissues.net/writers/irv/irv_172responsetocondic.html">http://www.lifeissues.net/writers/irv/irv_172responsetocondic.html</a>;
also, Irving, <span
style="font-family: 'Arial','sans-serif'; font-size: 10pt;">Condic’s
‘Pre-Zygote’ Error in ‘When Does Human Life Begin?’” (November 18,
2008), at:<span style=""> </span><a class="moz-txt-link-freetext"
href="http://www.lifeissues.net/writers/irv/irv_134maureencondic1.html">http://www.lifeissues.net/writers/irv/irv_134maureencondic1.html</a></span></span></font></div>
<div><font face="Calisto MT"> </font></div>
<div><font face="Calisto MT">(2) <strong>iPS research, as well as
most other similar types of research, require the use of "biological
materials" that are derived originally from human embryos and human
fetuses and then used throughout these experiments .</strong> This has
been acknowledged by these researchers themselves. That is, even aside
from the very real possibility that real living human embryos might be
"accidentally" reproduced during the iPS process, the fact remains that
bits and pieces of human embryos and fetuses are used throughout these
experiments (e.g., in the media used, the feeder cells used, the
"controls" in assays and machines used, etc.). Therefore, such
research could hardly claim that it was "free" of the unethical
destruction of any human embryos and fetuses. This concern about the
use of human embryonic and fetal "biological materials" in iPS stem
cell research holds for related research as well, such as somatic cell
nuclear transfer (SCNT), ANT, OAR, etc.</font></div>
<div><font face="Calisto MT"> </font></div>
<div><font face="Calisto MT">(3) It should also be pointed out in
fairness that the quote attributed to Debi Vinnedge (Executive Director
of Children of God For Life) as stated in the article below is also not
completely accurate. (On the other hand, these scientific "details"
are often difficult for those with little scientific background, like
reporters and most other people, to comprehend). Debi Vinnedge is
quoted as saying that "the study wasn't particularly helpful in
resolving moral issues surrounding stem-cell research because <strong><u>both
types of cells start with the aborted fetus</u></strong>." This
interpretation of what was said to the reporter could be misleading,
because, as Ms Vinnedge knows well, neither iPS research nor human
embryo research literally begin with an "aborted fetus". Rather, the
point Ms Vinnedge was trying to make, and as she so stated to the
reporter, was that <strong>"<u>both involve the destruction of
innocent human beings</u>."</strong> Ms Vinnedge explained to the
reporter that whether or not embryos were continuously destroyed in a
specific research protocol was not the issue; one had to destroy
embryos and fetuses in order to produce the embryonic cell lines
used that specific research protocol to begin with. She thus explained
that <span style="" lang="EN">"From a moral perspective, there's no
difference between embryonic and reprogrammed adult stem cell
research because scientists used embryonic stem cells and/or aborted
fetal cell lines <em>in order to accomplish the reprogramming</em>,"
Similarly, she </span>also pointed out to the reporter that the Bush
decision on using only those existing embryonic stem cells for federal
funding was still morally wrong simply because embryos had to have been
destroyed somewhere along the line -- it's just that tax dollars were
not used for the actual initial destruction. [Personal communication]
For an in-depth analysis of both the scientific and ethical concerns
surrounding iPS research, see Irving, <span
style="font-family: 'Arial','sans-serif'; font-size: 10pt;"><strong>“Ethical
and Scientific Concerns About Induced Pluripotent Stem Cell Research --
Yamanaka and Thomson”</strong></span><span
style="font-family: 'Arial','sans-serif'; font-size: 10pt;"> (June 1,
2008), at: <a
href="http://www.lifeissues.net/writers/irv/irv_127concerns.html">http://www.lifeissues.net/writers/irv/irv_127concerns.html</a>. --
DNI]]</span></font></div>
<div><font face="Calisto MT"> </font></div>
<div>
<div>
<p style="margin: 0in 0in 0pt;" class="MsoNormal"><font
face="Calisto MT" size="3"><a class="moz-txt-link-freetext"
href="http://www.washingtontimes.com/news/2010/jul/19/adult-stem-cells-said-to-forget-retooling/">http://www.washingtontimes.com/news/2010/jul/19/adult-stem-cells-said-to-forget-retooling/</a></font></p>
<p style="margin: 0in 0in 0pt;" class="MsoNormal"><font
face="Calisto MT"><o:p><font size="3"> </font></o:p></font></p>
<p style="margin: 0in 0in 0pt;" class="MsoNormal"><font
face="Calisto MT" size="3">WashingtonTimes.com</font></p>
<p style="margin: 0in 0in 0pt;" class="MsoNormal"><font
face="Calisto MT"><span style="" lang="EN"><font size="3">Monday, July
19, 2010</font></span></font></p>
<p style="margin: 0in 0in 0pt;" class="MsoNormal"><small><font
face="Calisto MT"><b><span style="font-size: 24pt;" lang="EN">Adult
stem cells said to 'forget' retooling<o:p></o:p></span></b></font></small></p>
<p style="margin: 0in 0in 0pt;" class="MsoNormal"><font
face="Calisto MT"><b><span style="font-size: 18pt;" lang="EN"><small>Embryonic
alternative suffers setback</small><o:p></o:p></span></b></font></p>
<p style="margin: 0in 0in 0pt;" class="MsoNormal"><font
face="Calisto MT"><span style="" lang="EN"><font size="3">By </font><a
title="http://www.washingtontimes.com/staff/valerie-richardson/"
href="http://www.washingtontimes.com/staff/valerie-richardson/"><font
size="3">Valerie Richardson</font></a><font size="3"> and </font><a
title="http://www.washingtontimes.com/staff/kathryn-watson/"
href="http://www.washingtontimes.com/staff/kathryn-watson/"><font
size="3">Kathryn Watson</font></a></span></font></p>
<p style="margin: 0in 0in 0pt;" class="MsoNormal"><font
face="Calisto MT"><o:p><font size="3"> </font></o:p></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">Reprogrammed
adult stem cells may not be as useful an alternative to controversial
embryonic stem-cell research as had been hoped, researchers found in
two articles published Monday.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">Researchers
at Children's Hospital Boston and Johns Hopkins University published an
article online in the prestigious journal Nature finding that such
adult stem cells remain fundamentally different from embryonic stem
cells and are no better at curing diseases in mice.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">Many
in the medical community and among pro-lifers have hoped harvesting
embryonic cells, which destroys the days-old human embryos and has
provoked intense ethical and moral criticism, could be avoided if
scientists could manipulate adult cells to act as if they were
embryonic stem cells.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">Called
"induced pluripotent stem cells" (or iPS), the altered adult cells
"forget" they were once cells naturally "programmed" to become liver
cells, lung cells, skin cells, etc. This would make them,
theoretically, as useful as embryonic cells for a variety of miracle
cures, especially for degenerative diseases such as Alzheimer's.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">It
turns out, the studies say, that they don't forget.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">"Our
data indicate that nuclear transfer [from embryonic stem cells] is more
effective at establishing the ground state of pluripotency than
factor-based reprogramming [of adult stem cells], which can leave an
epigenetic memory of the tissue of origin that may influence efforts at
directed differentiation for applications in disease modelling or
treatment," the article's findings stated.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">A
second, separate group of scientists led by Konrad Hochedlinger, a
stem-cell biologist at Massachusetts General Hospital Center for
Regenerative Medicine, published similar findings Monday in Nature
Biotechnology. That group said the adult cells obtained from mice
exhibited distinct patterns that could not be erased.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">Kitai
Kim, a postdoctoral fellow and one of the leading researchers on the
project published in Nature, explained that older cells are more set in
their ways and difficult to reprogram. His group worked with mice,
reprogramming different kinds of cells with varying results.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">The
needed DNA change "was incompletely reset in [reprogrammed adult] cells
compared to nuclear-transfer stem cells," said co-senior author Andrew
Feinberg. "This paper opens our eyes to the restricted lineage of iPS
cells. ... The lineage restriction by tissue of origin is both a
blessing and a curse. You might want lineage restriction in some cases,
but you may also have to do more work to make the iPS cells more
totally pluripotent."<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">Those
who oppose using embryos for stem-cell research have long argued in
favor of replacing them with adult stem cells. Critics have argued that
embryonic stem cells are scientifically superior to adult stem cells.
And the researchers said the findings demonstrate that the scientific
focus needs to be on embryonic stem-cell research.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">Arthur
Caplan, director of the Center for Bioethics at the University of
Pennsylvania, said the results of the study weren't surprising from a
scientific perspective, but could still have enormous implications for
future research.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">"A
giant balloon of enthusiasm just got the air let out of it," said Mr.
Caplan.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">"What
this shows is that ideology and values are no substitute for science,"
he said. "The science on this is still early, and the values and moral
beliefs are going to have to wait until the science has told us what's
possible."<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">Debi
Vinnedge, executive director of the Children of God for Life, which
opposes using embryonic stem-cell research, said the study wasn't
particularly helpful in resolving moral issues surrounding stem-cell
research because both types of cells start with the aborted fetus.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">"From
a moral perspective, there's no difference between embryonic and
reprogrammed adult stem cells because scientists used embryonic stem
cells and/or aborted fetal cell lines in order to accomplish the
reprogramming," Ms. Vinnedge said.<o:p></o:p></font></span></font></p>
<p><font face="Calisto MT"><span style="" lang="EN"><font size="3">The
research did show, however, that while reprogrammed stem cells may not
be as versatile as embryonic ones, they can still be quite useful.<o:p></o:p></font></span></font></p>
<font face="Calisto MT"><span
style="font-family: 'Times New Roman','serif'; font-size: 12pt;"
lang="EN">Thousands of patients around the world have been treated
with adult stem cells, but no humans as of yet have been given cells
derived from embryos in an approved trial.</span></font></div>
<div><font face="Calisto MT"> </font><br>
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<p><small>*** PFLI is the only pharmacy association which is
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It represents thousands of pharmacists and many lay supporters
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<br>
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excerpts
<br>
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<p
style="font-family: verdana; font-style: normal; font-variant: normal; font-weight: normal; font-size: 9pt; line-height: 11pt; font-size-adjust: none; font-stretch: normal;"><a
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Database (VPS): 100212-0, 02/12/2010<br>
Tested on: 2/12/2010 9:30:47 AM<br>
<font color="gray">avast! - copyright (c) 1988-2010 ALWIL Software.</font></p>
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